Why You’ll Love Grilled Mesquite Chicken Sandwich Recipe
If you’re a fan of smoky, grilled flavors, this sandwich is sure to be a hit. The mesquite seasoning infuses the chicken with a deep, slightly sweet and earthy taste that’s hard to resist. It’s quick to prepare, easy to customize, and great for serving a crowd or just upgrading your lunch routine. Plus, it’s a satisfying meal that feels indulgent without being overly complicated.
Ingredients
(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)
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Boneless, skinless chicken breasts
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Mesquite seasoning
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Olive oil
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Hamburger buns or sandwich rolls
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Lettuce
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Tomato slices
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Red onion (optional)
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Pickles (optional)
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Cheese slices (optional – cheddar, provolone, or pepper jack work well)
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Mayonnaise, BBQ sauce, or your favorite sandwich spread
Directions
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Preheat your grill to medium-high heat.
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Pound the chicken breasts to an even thickness for even cooking.
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Rub the chicken breasts with olive oil, then coat generously with mesquite seasoning.
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Place the chicken on the grill and cook for 5–7 minutes per side, or until the internal temperature reaches 165°F and the chicken has nice grill marks.
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Toast the buns on the grill during the last minute of cooking.
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Assemble the sandwich: Spread your desired condiments on the buns, add grilled chicken, lettuce, tomato slices, and any optional toppings like cheese, onions, or pickles.
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Serve hot and enjoy immediately.
Servings and timing
This recipe makes 4 sandwiches.
Prep time: 10 minutes
Cook time: 15 minutes
Total time: 25 minutes
Variations
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Spicy version: Add a dash of cayenne pepper or chipotle powder to the seasoning.
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Tex-Mex twist: Top with guacamole, jalapeños, and pepper jack cheese.
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Healthier option: Serve on a whole wheat bun or in a lettuce wrap.
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BBQ version: Brush the chicken with your favorite BBQ sauce during the last few minutes of grilling.
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Cheesy melt: Add a slice of cheese while the chicken is still hot on the grill to let it melt perfectly.
Storage/Reheating
Store leftover grilled chicken in an airtight container in the refrigerator for up to 3 days. To reheat, warm in a skillet over medium heat until heated through, or microwave for about 1 minute. Assemble the sandwich fresh to keep the texture of the bread and veggies intact. For freezing, store only the grilled chicken wrapped tightly in foil or a freezer-safe container for up to 2 months. Thaw overnight in the fridge before reheating.
FAQs
How do I keep the chicken from drying out on the grill?
Pounding the chicken to an even thickness and not overcooking it are key. Using a meat thermometer helps ensure it’s perfectly cooked.
Can I make this sandwich without a grill?
Yes, you can cook the chicken on a stovetop grill pan or in a skillet. You can also bake it in the oven or use an air fryer.
What is mesquite seasoning?
Mesquite seasoning is a smoky spice blend often used in barbecue. It typically includes paprika, garlic powder, onion powder, brown sugar, and natural smoke flavor.
Can I marinate the chicken before grilling?
Absolutely. Marinate in olive oil and mesquite seasoning (or add lemon juice or vinegar for extra flavor) for 30 minutes to 2 hours before grilling.
What are the best buns for this sandwich?
Brioche buns, hamburger buns, ciabatta rolls, or pretzel buns work great. Choose a bun that can hold up to juicy chicken and toppings.
Is this sandwich spicy?
Mesquite seasoning is typically mild. If you want more heat, add spicy toppings or extra seasoning.
Can I use chicken thighs instead of breasts?
Yes, boneless, skinless chicken thighs work well and stay juicy. Just adjust the cook time slightly.
What sides go well with this sandwich?
Serve with fries, coleslaw, sweet potato chips, or a simple green salad.
How can I make this sandwich dairy-free?
Skip the cheese and use a dairy-free spread or condiment. Make sure your buns are also dairy-free.
Can I prep this ahead of time?
Yes. Grill the chicken in advance and store it in the fridge. Assemble the sandwiches just before serving for the best texture.
Conclusion
This Grilled Mesquite Chicken Sandwich is a delicious way to enjoy bold, smoky flavors in a handheld meal. With simple ingredients and easy prep, it’s perfect for grilling season or a quick, flavorful dinner any time of year. Whether you go classic or try one of the tasty variations, it’s sure to become a favorite.
